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Wuhan Chemstan Biotechnology Co., Ltd.

武漢科斯坦生物科技有限公司

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Ruplizumab ( 盧利珠單抗 )
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產品名稱:

Ruplizumab ( 盧利珠單抗 )

NO.
017
貨號:
CSD00002
中文名稱
盧利珠單抗
英文名詞
Ruplizumab
CAS號
220651-94-5
產品貨號:
CSD00002
貨期:
現貨
價格與訂購:
2480.00
數量
-
+
庫存:
300
沒有此類產品
產品信息
如何訂購

貨號(Catalog No.)

CSD00002

通用名INN

Ruplizumab

純度(Purity)

>95%

濃度( Concentration)

1mg/ml

Formulation

PBS buffer PH7.5

Source

CHO cells

內毒素(Endotoxin level)

Please contact with the lab for this information.

生物活性

產品描述(Description)

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.Ruplizumab is an anti-CD40L monoclonal antibody.The binding of CD40 to its ligand,CD40L is a critical element in T cell activation.In systemic lupus erythematosus,CD40L is over-expressed on T cells, B cells and monocytes.

別名(Alternative names)

BG-9588,hu5c8

靶點;物種(Specificity target name;species)

CD40LG[Homo sapiens]

靶點背景信息(Target information)

Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

種類(Species)

Humanized

受體鑒定(Receptor identification)

IgG1-kappa

化學信息

分子量(MV)

145448.00 Da

CAS

220651-94-5

存儲條件(Storage)

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.

Note

For research use only .

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