Alemtuzumab ( 阿侖珠單抗 )

貨號（Catalog No.）

CSD00001

通用名INN

Alemtuzumab

純度(Purity)

>95%

濃度( Concentration)

1mg/ml

Formulation

PBS buffer PH7.5

Source

CHO cells

內毒素(Endotoxin level)

Please contact with the lab for this information.

生物活性

產品描述(Description)

Alemtuzumab is a humanized monoclonal antibody against CD52,an antigen found on the surface of normal and malignant lymphocytes.

別名(Alternative names)

Campath-1H,LDP-03

靶點;物種(Specificity target name;species)

CD52[Homo sapiens]

靶點背景信息(Target information)

Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

種類(Species)

Humanized

受體鑒定(Receptor identification)

IgG1-kappa

化學信息

分子量(MV)

150000.00 Da

CAS

216503-57-0

存儲條件(Storage)

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.

Note

For research use only .