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Wuhan Chemstan Biotechnology Co., Ltd.

武漢科斯坦生物科技有限公司

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Bevacizumab ( 貝伐珠單抗 )
瀏覽量:
產品名稱:

Bevacizumab ( 貝伐珠單抗 )

NO.
005
貨號:
CSD00004
中文名稱
貝伐珠單抗
英文名詞
Bevacizumab
CAS號
216974-75-3
產品貨號:
CSD00004
貨期:
現貨
價格與訂購:
2480.00
數量
-
+
庫存:
300
沒有此類產品
產品信息
如何訂購

貨號(Catalog No.)

CSD00004

通用名INN

Bevacizumab

純度(Purity)

>95%

濃度( Concentration)

1mg/ml

Formulation

PBS buffer PH7.5

Source

CHO cells

內毒素(Endotoxin level)

Please contact with the lab for this information.

生物活性

產品描述(Description)

Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.Bevacizumab, a humanized monoclonal antibody,specifically binds to all VEGF-A isoforms with high affinity.

別名(Alternative names)

12-IgG1,F(ab)-12 IgG1,Fab-12 IgG1,rhuMAb-VEGF

靶點;物種(Specificity target name;species)

VEGFA[Homo sapiens]

活性研究(體外/體內研究)(Activity in vitro)

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2. Experimental analysis shows that the EC50 of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC50 value of 0.047±0.0081 μg/mL.

種類(Species)

Humanized

受體鑒定(Receptor identification)

IgG1-kappa

化學信息

分子量(MV)

149000.00 Da

CAS

216974-75-3

存儲條件(Storage)

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.

Note

For research use only .

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